Medical Director, Oncology Clinical Development

Medical Director, Oncology Clinical Development The Medical Director, Oncology Clinical Development will report to the Executive Medical Director, Clinical Development Lead (CDL) and is responsible for leading clinical research activities that advance GSK’s oncology portfolio, engaging with scientific and medical leaders, and managing relationships with Key External Experts. This position requires an on-site, office-based presence 2 to 3 days a week in the UK (London or Stevenage); Switzerland (Zug); US (Upper Providence, PA or Waltham, MA); or Poland (Warsaw). Key Responsibilities Collaborate with medical directors, scientists, regulatory professionals, biostatisticians and senior leaders in a complex matrix environment to develop and execute phase 1‑3 interventional clinical trials.

Ensure high‑quality protocol development aligned with the Clinical Development Plan to determine a medicine’s efficacy, safety profile, differentiation and value to patients. Contribute to end‑to‑end clinical trials (protocol concept to final study report) to ensure scientific integrity and timely delivery, incorporating global considerations in decision making. Interpret and summarize study results to define safety, efficacy, PK/PD, patient‑reported outcomes and applicability to the target population.

Assume medical responsibility for clinical trials, actively monitor studies, assess patient eligibility, address study‑design issues, and manage urgent safety queries (including Safety/PV). Oversee medical review of clinical‑trial data, including direct review and delegated oversight; supervise blinded review of data packages for IDMCs. Collaborate with pharmacovigilance to monitor safety data for active studies.

Participate in authoring clinical‑study reports and regulatory documents with Regulatory Affairs, CMC, Toxicology, Research and Pharmacology teams. Work with Principal Investigators to evaluate and assess publications (abstracts, posters, manuscripts) related to clinical data. Network extensively to forge strategic partnerships with thought leaders, supporting GSK’s vision.

Understand biological mechanisms, clinical strategy, scientific interpretation of disease and target‑based literature. Serve as a core member of the Clinical Matrix Team for one or more assets in development. Represent Clinical Development in disease‑area strategy, integrated evidence, and medical‑affairs strategy teams.

Take part in Oncology Clinical Development‑wide initiatives and workstreams as appropriate. Basic Qualifications Medical degree with board certification/eligibility or registration in medical oncology, hematology, hematology/oncology, general surgery, internal medicine, or pathology. Experience in the pharmaceutical/biotechnology industry, clinical academic medicine, or clinical medical practice settings in oncology.

Experience conducting or participating in clinical trials (investigator‑initiated, company‑sponsored, or cooperative group) and publishing results. Preferred Qualifications Medical degree with board or registration qualifications in medical oncology, hematology, or pathology. Board or registration certified or eligible physician with a PhD degree.

Experience in Lung or Head & Neck Oncology trials, including study design, data review, and the full clinical‑development process. Knowledge of regulatory requirements for registration, GCP principles, and adherence to them. Robust knowledge of disease‑specific research priorities, public health needs, competitor landscape, clinical practice trends and treatment‑guideline evolution.

Salary and Benefits Annual base salary ranges $222,750 to $371,250 for designated US locations (Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA). The annual base salary in Poland ranges from PLN 455,250 to PLN 758,750 gross. The position also offers an annual bonus, eligibility to participate in a share‑based long‑term incentive program, health‑care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.

Equal Opportunity Employer & Accommodation GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at usrecruitment.adjustments@gsk.com. #J-18808-Ljbffr