Manager Continuous Improvement and Production Support

Job Title: Manager Continuous Improvement and Production Support Location: Pearl River, NY About the Job This combination technical‑leadership role combines hands‑on expertise in biologics manufacturing with strategic team management to drive operational excellence across our Flublok production processes. You will lead a team of Subject Matter Experts while providing direct technical oversight of upstream and downstream operations, ensuring GMP compliance, and spearheading continuous improvement initiatives that enhance process efficiency, yield, and quality. The ideal candidate thrives in a fast‑paced, regulated environment where technical problem‑solving meets people development, and where your leadership directly impacts our mission to deliver life‑saving healthcare solutions to patients worldwide.

About Sanofi We deliver 4.3 billion healthcare solutions to people every year, thanks to the flawless planning and meticulous eye for detail of our Manufacturing & Supply teams. With your talent and ambition, we can do even more to protect people from infectious diseases and bring hope to patients and their families. Main Responsibilities Team Leadership & Development Lead, mentor, and develop a team of Subject Matter Experts across upstream and downstream manufacturing operations Manage a Continuous Improvement team focused on process optimization and operational excellence Coach team members on troubleshooting strategies, root‑cause analysis methodologies, and process improvement techniques Foster a culture of collaboration, accountability, and continuous learning Manufacturing Operations & Technical Oversight Provide technical leadership and hands‑on support for Flublok drug substance manufacturing processes Oversee upstream operations including cell scale‑up, media preparation, and protein production Oversee downstream operations including purification and buffer preparation Ensure all manufacturing activities comply with GMP regulations and internal quality standards Serve as a technical resource for complex process troubleshooting and deviation investigations Continuous Improvement & Change Management Drive continuous improvement initiatives to enhance process efficiency, yield, and quality Open, author, and drive change controls through completion in accordance with quality systems Lead root‑cause analysis investigations using structured methodologies (e.g., 5 Whys, Fishbone, FMEA) Identify and implement process improvements and efficiency gains across manufacturing operations Documentation & Compliance Draft, review, and approve technical documents including SOPs, batch records, protocols, and reports Ensure documentation practices meet GMP and regulatory requirements Support regulatory inspections and audits as needed About You Basic Qualifications Bachelor's degree in biology, Biomedical Engineering, Mechanical Engineering, Biological Engineering, or related scientific discipline Master's degree preferred 7+ years of experience in biopharmaceutical manufacturing or process development, with demonstrated hands‑on expertise in upstream operations (cell growth and scale‑up), downstream operations (purification and buffer preparation), and analytical techniques such as chromatography.

Minimum 3+ years of people management experience. Demonstrated experience in Pharmaceutical GMP manufacturing environments. Technical Skills Process development experience in biologics manufacturing Strong background in root‑cause analysis and structured problem‑solving methodologies Single Use Technology (SUT) systems and operations Gas chromatography and analytical techniques Media preparation and buffer preparation Protein production processes Cell culture and cell scale‑up operations Upstream and/or downstream biologics manufacturing Soft Skills Proven ability to lead, coach, and develop high‑performing teams Strong change control management experience Excellent written and verbal communication skills Ability to balance strategic leadership with hands‑on technical support Strong organizational and project management skills Collaborative mindset with ability to work cross‑functionally Preferred Qualifications Experience with Flublok or recombinant protein vaccine manufacturing Experience with insect cell culture systems (e.g., Sf9, expresSF+) Lean Six Sigma certification or equivalent continuous improvement training Why choose us?

Bring the miracles of science to life alongside a supportive, future‑focused team. Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally. Enjoy a thoughtful, well‑crafted rewards package that recognizes your contribution and amplifies your impact.

Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high‑quality healthcare, prevention and wellbeing programs and at least 14 weeks’ gender‑neutral parental leave. Shape the future of medicine and vaccine delivery with cutting‑edge technology, ensuring seamless launches and a resilient global supply. Power industry‑leading performance by leveraging digital, data, and AI‑driven innovation – at speed and scale Transform lives worldwide by delivering life‑changing treatments anywhere, anytime.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Aff… (full legal statement omitted for brevity). All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here. #J-18808-Ljbffr